All Skills

Manage vendor relationships, track performance, negotiate contracts, and optimize procurement

Shell script workflow guidelines. Activate when working with shell scripts (.sh), bash scripts, or shell-specific tooling like shellcheck, shfmt.

Observe: Specifications

Orient: Build

Design vector similarity search systems for semantic retrieval at scale

Perform company and asset valuations using DCF, comparables, precedent transactions, and other methodologies

KEGG-based disease-drug-variant research using KEGG Disease, Drug, Network, and Variant databases. Covers disease gene lookup, drug-target analysis, disease-gene-drug network exploration, and variant annotation. Use when users ask about KEGG disease entries, KEGG drug targets, disease-variant-drug relationships, or KEGG network analysis.

Analyze mass spectrometry proteomics data including protein quantification, differential expression, post-translational modifications (PTMs), and protein-protein interactions. Processes MaxQuant, Spectronaut, DIA-NN, and other MS platform outputs. Performs normalization, statistical analysis, pathway enrichment, and integration with transcriptomics. Use when analyzing proteomics data, comparing protein abundance between conditions, identifying PTM changes, studying protein complexes, integrating protein and RNA data, discovering protein biomarkers, or conducting quantitative proteomics experiments.

Retrieves protein structure data from RCSB PDB, PDBe, and AlphaFold with protein disambiguation, quality assessment, and comprehensive structural profiles. Creates detailed structure reports with experimental metadata, ligand information, and download links. Use when users need protein structures, 3D models, crystallography data, or mention PDB IDs (4-character codes like 1ABC) or UniProt accessions.

Data Engineer Agent

Update Maestro Documentation

Prompt Command

Observe: Story Task, Specs, Implementation

Studio de geracao de imagens inteligente — roteamento automatico entre ai-studio-image (fotos humanizadas/influencer) e stability-ai (arte/ ilustracao/edicao). Detecta o tipo de imagem solicitada e escolhe o modelo ideal automaticamente.

Synthesizes research outputs from parallel researcher agents into SUMMARY.md. Spawned by /gsd:new-project after 4 researcher agents complete.

Research plant genes, pathways, and species using PlantReactome, Ensembl Plants, POWO, UniProt, KEGG, and literature tools. Covers plant pathway analysis, gene function annotation, species identification, crop genomics, and comparative plant biology. Use when asked about plant genes, Arabidopsis, crop improvement, plant pathways, plant metabolism, photosynthesis, plant development, or plant species identification.

Setup paperpipe agent integration. Use when user wants to add papi to a project's CLAUDE.md/AGENTS.md or initialize paper support.

Calculate and optimize unit economics including CAC, LTV, payback periods, and contribution margins

Expert guide for building beautiful, responsive UI with React, Tailwind CSS, Shadcn/ui, and modern design patterns. Use when creating components, layouts, animations, or styling.

Predict patient response to immune checkpoint inhibitors (ICIs) using multi-biomarker integration. Given a cancer type, somatic mutations, and optional biomarkers (TMB, PD-L1, MSI status), performs systematic analysis across 11 phases covering TMB classification, neoantigen burden estimation, MSI/MMR assessment, PD-L1 evaluation, immune microenvironment profiling, mutation-based resistance/sensitivity prediction, clinical evidence retrieval, and multi-biomarker score integration. Generates a quantitative ICI Response Score (0-100), response likelihood tier, specific ICI drug recommendations with evidence, resistance risk factors, and a monitoring plan. Use when oncologists ask about immunotherapy eligibility, checkpoint inhibitor selection, or biomarker-guided ICI treatment decisions.

Plan and execute user-generated content campaigns that build community and authenticity

Expert guide for testing Next.js applications with Playwright, Jest, and React Testing Library. Use when writing tests, debugging test failures, or setting up test infrastructure.

Guidelines for multi-agent AI and learning projects with lesson-based structures. Activate when working with AI learning projects, experimental directories like .spec/, lessons/ directories, STATUS.md progress tracking, or structured learning curricula with multiple modules or lessons.

Act: Build